Population genetics of SalmonellaTyphimurium DT104: redefining a clonal model.
Perron, Gabriel*,1, Bell, Graham1, Quessy, Sylvain2, 1 McGill University, Montreal, Qc, Canada2 Universite de Montreal, St-Hyacinthe, Qc, Montreal
ABSTRACT- Developing effective strategies for the control of bacterial pathogens requires a good understanding of the invader's population structure. Since the evolution of transmissible bacteria is influenced by the genetic diversity present in a population, it is vital to properly recognize the community composition of that population. Yet, most studies of bacterial pathogens have focused on samples biased for highly adaptive clonal complexes such as antibiotic resistant or epidemic related isolates. We thus examined the genotypic diversity of Salmonella Typhimurium DT104 from non-disease associated isolates to actualize the clonal model associated with this important pathogen. The model provides valuable insight in the role community structure of bacterial populations plays in the evolution and dispersion of virulent genotypes into animal populations.
Key words: bacteria, community ecology, diversity, evolution
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