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ABDEL-RAHMAN, SULTANMP04-48 Response to neoadjuvant thermochemotherapy predicts long-term survival for patients with retroperitoneal/visceral soft-tissue sarcomas.
Wendtner, Clemens1, Abdel-Rahman, Sultan1, Baumert, Jens1, Falk, Martin1, Hiddemann, Wolfgang1, Issels, Rolf1,2, 1 2
FULL ABSTRACT
ABDOUL-CARIME, HASSANP09-122 Fundamental mechanism of DNA strand breaks induced by low-energy (<20eV) electrons .
Abdoul-Carime, Hassan1, Sanche, Léon 1, 1
FULL ABSTRACT
ABDOUL-CARIME, HASSANMS07-4 Fundamental mechanism of DNA strand breaks induced by low-energy (<20eV) electrons .
Abdoul-Carime, Hassan1, Sanche, Léon 1, 1
FULL ABSTRACT
AFT, REBECCAP08-108 Cytotoxic and Radiosensitizing Effects of 2-Deoxy-d-Glucose on Hela Cells.
Lin, Xiao1, Aft, Rebecca2, Spitz, Douglas3, Gius, David1, 1 2 3
FULL ABSTRACT
AFT, REBECCAMS11-1 Cytotoxic and Radiosensitizing Effects of 2-Deoxy-d-Glucose on Hela Cells.
Lin, Xiao1, Aft, Rebecca2, Spitz, Douglas3, Gius, David1, 1 2 3
FULL ABSTRACT
AHMED, MANSOORP26-354 Influence of BCL-2 overexpression on radiosensitizing effect of DIDOX in human prostate tumor cell line PC-3.
Inayat, Mohammed1,2, Mayhew, Christopher 2, Chendil, Damodaran3, Dey, Swatee3, Bond, Andy1, Mohiuddin, Mohammed3, Elford, Howard4, Gallicchio, Vincent2, Ahmed, Mansoor3, 1 2 3 4
FULL ABSTRACT
AHMED, MANSOORP18-213 Par-4, a pro-apoptotic gene, inhibits NFB activity resulting in the repression of radiation-induced bcl-2 expression leading to induction of radiosensitivity in human prostate cancer cells PC-3.
Chendil, Damodaran1, Das, Anindita1, Dey, Swatee1, Mohiuddin, Mohammed1, Rangnekar, Vivek1, Ahmed, Mansoor1, 1
FULL ABSTRACT
AHMED, MANSOORP18-214 EGR-1 mediates the radiation-induced proapoptotic action by transactivating bax in p53 mutant prostate cancer cell line DU-145.
Das, Anindita1, Chendil, Damodaran1, Dey, Swatee1, Mohiuddin, Mohammed1, Rangnekar, Vivek1, Ahmed, Mansoor1, 1
FULL ABSTRACT
AHMED, MANSOORP18-216 Restoration of TGF- signaling enhances radiosensitivity by altering the bcl-2: bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2 .
Alcock, Rachael1, Chendil, Damodaran1, Das, Anindita1, Dey, Swatee1, Venkatasubbarao, Kolaparthi2, Mohiuddin, Mohammed1, Freeman, James2, Ahmed, Mansoor1, 1 2
FULL ABSTRACT
AHMED, MANSOORP28-383 Increased PSA mRNA expression during brachytherapy procedure in peripheral blood of patients with prostate cancer.
Siddiqua, Ayisha1, Chendil, Damodaran1, Das, Anindita1, Rowland, Randall2, Ahmed, Mansoor1, Mohiuddin, Mohammed1, 1 2
FULL ABSTRACT
AHMED, MANSOORMS06-4 EGR-1 mediates the radiation-induced proapoptotic action by transactivating bax in p53 mutant prostate cancer cell line DU-145.
Das, Anindita1, Chendil, Damodaran1, Dey, Swatee1, Mohiuddin, Mohammed1, Rangnekar, Vivek1, Ahmed, Mansoor1, 1
FULL ABSTRACT
AHMED, MANSOORMS06-8 Restoration of TGF- signaling enhances radiosensitivity by altering the bcl-2: bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2 .
Alcock, Rachael1, Chendil, Damodaran1, Das, Anindita1, Dey, Swatee1, Venkatasubbarao, Kolaparthi2, Mohiuddin, Mohammed1, Freeman, James2, Ahmed, Mansoor1, 1 2
FULL ABSTRACT
AHMED, MANSOORMS14-5 Par-4, a pro-apoptotic gene, inhibits NFB activity resulting in the repression of radiation-induced bcl-2 expression leading to induction of radiosensitivity in human prostate cancer cells PC-3.
Chendil, Damodaran1, Das, Anindita1, Dey, Swatee1, Mohiuddin, Mohammed1, Rangnekar, Vivek1, Ahmed, Mansoor1, 1
FULL ABSTRACT
AHMED, MANSOORMS14-7 Increased PSA mRNA expression during brachytherapy procedure in peripheral blood of patients with prostate cancer.
Siddiqua, Ayisha1, Chendil, Damodaran1, Das, Anindita1, Rowland, Randall2, Ahmed, Mansoor1, Mohiuddin, Mohammed1, 1 2
FULL ABSTRACT
AHN, G-ONEP26-340 Radiation-activated prodrugs as hypoxia-selective cytotoxins: a novel cobalt(III):azaCBI-TMI complex.
Wilson, William1, Ahn, G-One1, Botting, Jane1, Ware, David1, Denny, William1, 1
FULL ABSTRACT
AHN, HAEEUNMP02-18 Effect of carboplatin in combination with hyperthermia on cell death in human retinoblastoma cell lines.
Park, SoRaInha University, Choi, EunKyungUlsan University, Ahn, HaeEunInha University, Rhee, YunHeeUlsan University, Ha, SungWhanSeoul National University, Lim, ByungUkInha University, Park, HeonJooInha University,
FULL ABSTRACT
AHRENS, MIRCOP14-179 Relationship between radiation-induced G1-arrest, dsb repair and cellular radiosensitivity in normal human fibroblasts.
Dikomey, Ekkehard1, Brammer, Ingo1, Kröger, Jan1, Ahrens, Mirco1, Overgaard, Jens2, 1 2
FULL ABSTRACT
AIGUEPERSE, JOCELYNEP06-81 Analysis by high density cDNA arrays of altered gene expression in human late radiation-induced intestinal fibrosis : a case report.
Vozenin-Brotons, Marie-Catherine1, François, Agnès 1, Lasser, Philipe2, Antoun, Sami2, Haie-Meder, Christine2, Lusinchi, Antoine2, Morice, Philipe2, Milliat, Fabien1, Aigueperse, Jocelyne1, 3, Girinsky, Théodore1, 2, 1 2 3
FULL ABSTRACT
AINSWORTH, JOHNP19-240 Molecular biomarkers induced by radiation exposure: application to radiation carcinogenesis and cancer chemoprevention.
Miller, Alexandra1, Ainsworth, John1, Seed, Thomas1, 1
FULL ABSTRACT
AKAZAWA, PAMELAP09-126 Skin Toxicity Associated With the Use of Extended Field Intensity Modulated Radiation Therapy (IMRT) in the Treatment of Head and Neck Cancer.
Xia, Ping1, Lee, Nancy1, Chuang, Cynthia1, Akazawa, Pamela1, Phillips, Theodore1, Poon, Ian1, Quivey, Jeanne1, Verhey, Lynn1, 1
FULL ABSTRACT
AL-BETERI, ABDULKARIMP20-247 Impaired induction of p53/p21 proteins in fibroblasts derived from AT, ATH and breast cancer patients.
Torres, Martha1, Paterson, Malcolm1, Al-Beteri, Abdulkarim1, Alsbeih, Ghazi1, 1
FULL ABSTRACT
AL-RASHID, SHAHNAZP05-64 Evidence for a direct role of the p53 protein in DNA-dsb repair.
Al-Rashid, Shahnaz1,3, Jalali, Farid1,3, Lilge, Lothar1,3, Bristow, Robert1,2,3, 1 3 2
FULL ABSTRACT
AL-RASHID, SHAHNAZMS13-6 Evidence for a direct role of the p53 protein in DNA-dsb repair.
Al-Rashid, Shahnaz1,3, Jalali, Farid1,3, Lilge, Lothar1,3, Bristow, Robert1,2,3, 1 3 2
FULL ABSTRACT
ALANIZ, ALEXS15-1 Elastography opens new frontiers for diagnostic imaging and thermal therapy monitoring.
Kallel, Faouzi1, Righetti, Raffaella1, Stafford, Jason2, Price, Roger3, Hirasaki, Ken1, Alaniz, Alex1, Krouskop, Thomas4, Hazle, John2, Garra, Brian5, Ophir, Jonathan1, 1 2 3 4 5
FULL ABSTRACT
ALBERT, DONNAL03 Genome evolution in human breast cancers: Mechanisms and consequences.
Gray, Joe1, Chin, Kwang-Yung 1, Kuo, Wen-Lin1, Jain, Ajay1, Phuchareon, Janyaporn1, Volik, Stas1, Albert, Donna 1, Pinkel, Daniel1, Collins, Colin1, Waldman, Fredric1, 1
FULL ABSTRACT
ALBERTSON, CHRISTOPHERP06-74 Modulation of radiation enteropathy by hirudin, a direct thrombin inhibitor.
Hauer-Jensen, Martin1, Zheng, Huaien1, Ou, Xuemei1, Albertson, Christopher1, Fink, Louis1, Herbert, Jean-Marc1, Wang, Junru1, 1
FULL ABSTRACT
ALBRIGHT, NORMP23-286 Computerized video time lapse (CVTL) analysis of human EJ30 cells x-irradiated in different phases of the cell cycle.
Chu, Kenneth1, Leonhardt, Edith1, Albright, Norm1, Dewey, William1, 1
FULL ABSTRACT
ALCOCK, RACHAELP18-216 Restoration of TGF- signaling enhances radiosensitivity by altering the bcl-2: bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2 .
Alcock, Rachael1, Chendil, Damodaran1, Das, Anindita1, Dey, Swatee1, Venkatasubbarao, Kolaparthi2, Mohiuddin, Mohammed1, Freeman, James2, Ahmed, Mansoor1, 1 2
FULL ABSTRACT
ALCOCK, RACHAELMS06-8 Restoration of TGF- signaling enhances radiosensitivity by altering the bcl-2: bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2 .
Alcock, Rachael1, Chendil, Damodaran1, Das, Anindita1, Dey, Swatee1, Venkatasubbarao, Kolaparthi2, Mohiuddin, Mohammed1, Freeman, James2, Ahmed, Mansoor1, 1 2
FULL ABSTRACT
ALLALUNIS-TURNER, JOANP08-109 Variation in response to hypoxic stress in human glioma.
Allalunis-Turner, Joan1,2, Turcotte, Laurina1, Franko, Allan1,2, Parliament, Matthew1,2, 1 2
FULL ABSTRACT
ALLEN-HOFFMANN, LYNNP28-372 Impact of egf-receptor blockade on squamous cell carcinoma radiation response in the niks normal tissue microenvironment tumor model.
Pickart, Michael1,2, Bachman, Timothy1, Allen-Hoffmann, Lynn1,2, Harari, Paul1,2, 1 2
FULL ABSTRACT
ALSBEIH, GHAZIP20-247 Impaired induction of p53/p21 proteins in fibroblasts derived from AT, ATH and breast cancer patients.
Torres, Martha1, Paterson, Malcolm1, Al-Beteri, Abdulkarim1, Alsbeih, Ghazi1, 1
FULL ABSTRACT
ALSBEIH, GHAZIP24-301 Examination of gene expression differences in human fibroblasts predictive of therapeutic outcome by microarray analysis.
Giri, Uma1, Singh, Sheela1, Alsbeih, Ghazi1, Brock, Bill1, Story, Michael1, 1
FULL ABSTRACT
ALSUBAEL, MOHAMMADP23-287 P53 and the Effects of Radiation on the Progression of Human Fibroblasts Released form Density-Inhibited Culture.
Bedford, Joel1, Alsubael, Mohammad1, 1
FULL ABSTRACT
ALTSHULER, DAVIDS014-1 Genomic approaches to the genetics of common disease.
Altshuler, David1,2,3, 1 2 3
FULL ABSTRACT
AMEZIANE, ALIMP03-36 Assessment of the SAR steering feasibility of the Sigma-Eye applicator using the Schottky diode sheet.
van Rhoon, Gerard1, Ameziane, Ali1, van den Biggelaar, Adrie1, Rietveld, Paul1, van der Zee, Jacoba1, 1
FULL ABSTRACT
AMORINO, GEORGEP27-368 EGFR-dependence of radiation-induced transcription factor activation.
Amorino, George1, Mikkelsen, Ross1, Valerie, Kristoffer1, Dent, Paul1, Hewit, Theodore1, Schmidt-Ullrich, Rupert1, 1
FULL ABSTRACT
AMOSCATO, ANDREWP08-106 Protective role of Bcl-2 in metabolic oxidative stress-induced cell death.
Lee, Yong1, Chen, Jenn2, Amoscato, Andrew1, Bennouna, Jaafar1, Spitz, Douglas3, Suntharalingam, Mohan4, Rhee, Juong4, 1 2 3 4
FULL ABSTRACT
AMUNDSON, SALLYP19-235 Identification of potential radiation biomarkers in mice irradiated in vivo.
Amundson, Sally1, Bittner, Michael2, Meltzer, Paul2, Trent, Jefferey2, Koch-Paiz, Christine1, Fornace, Albert1, 1 2
FULL ABSTRACT
ANDERSON, RHONAS19-2 Chromosomal biomarkers of exposure to high-LET radiation revealed by FISH and M-FISH techniques.
Anderson, Rhona1, 1
FULL ABSTRACT
ANDERSON, RHONAP29-386 Are -particle-induced complex chromosome aberrations induced directly by the particle track or via an indirect bystander effect?
Anderson, Rhona1, Clapham, Peter1, Bristow, Anna1, Goodhead, Dudley1, 1
FULL ABSTRACT
ANDERSON, ROBINP18-228 Hsp72 inhibits stress-induced apoptosis by targeting the activation of effector caspases.
Buzzard, Katherine1, Killender, Marilyn1, Redvers, Richard1, Anderson, Robin1, 1
FULL ABSTRACT
ANG, KIANP27-367 C225 antiepidermal growth factor receptor (EGFR) antibody enhances human tumor xenograft response to radiation (XRT) and docetaxel (DOC).
Nasu, Sachiko1, Hunter, Nancy1, Mason, Kathryn1, Fan, Zhen1, Ang, Kian1, Milas, Luka1, 1
FULL ABSTRACT
ANSCHER, MITCHELLP25-326 A Dual Effect of the Novel Synthetic SuperOxide Dismutase (SOD) Mimetics In Radiation Therapy.
Vujaskovic, Zeljko1, Batinic-Haberle, Ines1, Spasojevic, Ivan 1, Samulski, Thaddeus1, Fridovich, Irwin1, Dewhirst, Mark1, Anscher, Mitchell1, 1
FULL ABSTRACT
ANTOUN, SAMIP06-81 Analysis by high density cDNA arrays of altered gene expression in human late radiation-induced intestinal fibrosis : a case report.
Vozenin-Brotons, Marie-Catherine1, François, Agnès 1, Lasser, Philipe2, Antoun, Sami2, Haie-Meder, Christine2, Lusinchi, Antoine2, Morice, Philipe2, Milliat, Fabien1, Aigueperse, Jocelyne1, 3, Girinsky, Théodore1, 2, 1 2 3
FULL ABSTRACT
APPELLA, ETTOREP05-62 Detecting p53-Induced DNA bending and Twisting by Iodine-125 Radioprobing.
Karamychev, Valeri 1, Panyutin, Igor1, Mazur, Sharlyn2, Appella, Ettore2, Zhurkin, Victor2, Neumann, Ronald1, 1 2
FULL ABSTRACT
APPELLA, ETTORES28-1 Cross-talk Between Stress-Inducible Kinases and the Cell Cycle Machinery.
Bulavin, Dmitry1, Higashimoto, Yuichiro 2, Appella, Ettore2, Fornace, Albert1, 1 2
FULL ABSTRACT
APPELLA, ETTOREP23-291 Role of p53 post-translational modifications in cHa-ras induced senescence of primary human cells.
Bulavin, Dmitry1, Demidov, Oleg1, Saito, Shin'ichi1, Higashimoto, Yuichiro1, Fornace, Albert1, Appella, Ettore1, 1
FULL ABSTRACT
AQUINO-PARSONS, CHRISTINAP21-256 Pimonidazole binding in human tumors analyzed by flow and image analysis of single cells.
Olive, Peggy1, Luo, Chenmei1, Banath, Judit1, Durand, Ralph1, Raleigh, Jim2, Aquino-Parsons, Christina3, 1 2 3
FULL ABSTRACT
ARAVINDAN, NATARAJANP27-359 Rel/kB regulation in Induced Radioresistance.
Natarajan, Mohan 1, Aravindan, Natarajan1, Meltz, Martin1, Thomas, Charles1, Herman, Terence1, 1
FULL ABSTRACT
ARMOUR, ELWOODS04-2 Cytotoxic genes on the heat shock promoter.
Corry, Peter1, Borrelli, Micheal1, Armour, Elwood1, 1
FULL ABSTRACT
ARMOUR, ELWOODP07-96 Nitric Oxide Gene Therapy for Prostate Cancer.
Armour, Elwood1, McEachern, Donna1, 1
FULL ABSTRACT
ARMSTRONG, JEFFREYP18-227 Rotenone-induced G2/M cell cycle arrest and apoptosis via a caspase 3 dependent mechanism in PW cells.
Armstrong, Jeffrey1, Lecane, Philip1, Steinauer, Kirsten1, Peehl, Donna1, Knox, Susan1, 1
FULL ABSTRACT
ARTHUR, R. MARTINMP03-41 Estimation of Hyperthemic Temperatures from Backscattered Ultrasonic Energy.
Arthur, R. Martin1, Straube, William1, Moros, Eduardo1, 1
FULL ABSTRACT
ASANO, MAKOTOP28-375 Combined Effects of Anti-VEGF Neutralizing Antibody and Ionizing Radiation on Tumor Growth and Hypoxic Fraction.
Itasaka, Satoshi1, Oya, Natsuo1, Sasai, Keisuke2, Nihei, Keiji3, Asano, Makoto4, Hiraoka, Masahiro1, 1 2 3 4
FULL ABSTRACT
ASEA, ALEXZANDERMP02-14 Screening of chemical library in the process of novel anti-cancer drug discovery.
Lechpammer, Stanislav1, Asea, Alexzander1, Sherman, Michael2, Calderwood, Stuart1, 1 2
FULL ABSTRACT
ASEA, ALEXZANDERMP01-1 The effect of phosphorylation of HSF1 within its regulatory domain on trans-activation .
Wang, Xiaozhe1, Asea, Alexzander1, Xie, Yue1, Calderwood, Stuart 1, 1
FULL ABSTRACT
ASEA, ALEXZANDERMS03-3 The Chaperokine Effect.
Asea, Alexzander1, Calderwood, Stuart1, 1
FULL ABSTRACT
ASEA, ALEXZANDERMS06-7 The effect of phosphorylation of HSF1 within its regulatory domain on trans-activation .
Wang, Xiaozhe1, Asea, Alexzander1, Xie, Yue1, Calderwood, Stuart 1, 1
FULL ABSTRACT
ASHLEY, TIMOTHYS12-4 Inhibition of ATP synthesis on the surface of endothelial cells by angiostatin.
Kenan, Daniel1, Moser, Tammy1, Misra, Uma1, Ashley, Timothy1, Roy, July1, Pizzo, Salvatore1, 1
FULL ABSTRACT
ATENCIO, DAVIDP14-181 ATM Heterozygosity and Breast Cancer.
Rosenstein, Barry1, Atencio, David1, 1
FULL ABSTRACT
ATER COLLABORATION, ON BEHALF OF THEP16-200 Carbon ion relative biological effectiveness for normal and tumour human cell lines.
Grossi , Gianfranco1,2, ATER Collaboration, On behalf of the2, 1 2
FULL ABSTRACT
ATTIX, CHRISTINAP15-187 Adaptability response of ten human lymphoblastoid cell lines: Testing for reproducibility.
Sorensen, Karen1, Attix, Christina 1, Coleman, Matthew1, Wyrobek, Andrew1, Tucker, James1, 1
FULL ABSTRACT
ATTIX, CRISTINAS19-3 New approaches to detecting cytogenetic damage.
Tucker, James1, Christian, Allen1, Attix, Cristina1, Pattee, Melissa1, Sorensen, Karen1, 1
FULL ABSTRACT
AUERBACH, WOJTEKP24-302 Mrad9 Knockout ES cells and Mice.
Hopkins, Kevin1, Auerbach, Wojtek2, Zheng, Wei1, Hang, Haiying1, Joyner, Alexandra2, Lieberman, Howard1, 1 2
FULL ABSTRACT
AUSTIN, BRIANS26-1 Genomic instability, bystander effects and radiation risks: Implications for development of environmental protection strategies .
Mothersill, Carmel1, Seymour, Colin1, Lyng, Fiona1, Mulford, Alba2, Austin, Brian2, 1 2
FULL ABSTRACT
AVRUTSKAYA, ANNAS25-4 Transcription-Coupled Repair: A Multifunctional Signalling Pathway.
Leadon, Steven 1, Avrutskaya, Anna 1, Rauscher, Frank2, Ruffner, Heinz3, Verma, Inder3, 1 2 3
FULL ABSTRACT
AVRUTSKAYA, ANNAP24-309 BRCA1 and Transcription-Coupled Repair: Structure/Function Analysis .
Avrutskaya, Anna1, Ruffner, Heinz2, Verma, Inder2, Leadon, Steven1, 1 2
FULL ABSTRACT
AYDOGAN, BULENTP10-136 Consideration of steric hindrance in Monte Carlo modeling of OH radical attack on DNA.
Aydogan, Bulent 1, Marshall, David2, Swarts, Steven 3, Turner, James 4, Morabito, Brian 1, Bolch, Wesley1, 1 2 3 4
FULL ABSTRACT
AYDOGAN, BULENTMS12-3 Consideration of steric hindrance in Monte Carlo modeling of OH radical attack on DNA.
Aydogan, Bulent 1, Marshall, David2, Swarts, Steven 3, Turner, James 4, Morabito, Brian 1, Bolch, Wesley1, 1 2 3 4
FULL ABSTRACT
AYENE, IRAIMOUDIP08-112 Homeostatic regulation of protein thiol redox status, and the cellular response to ionizing radiation.
Tuttle, Stephen 1, Koch, Cameron1, Ayene, Iraimoudi1, Stamato, Thomas2, Biaglow, John1, 1 2
FULL ABSTRACT
AYENE, IRAIMOUDIP08-113 Role of vicinal protein thiols in the cellular radiation response.
Donahue, Jerremiah1, Tuttle, Stephen1, Ayene, Iraimoudi1, Koch, Cameron1, Biaglow, John1, 1
FULL ABSTRACT
AYENE, IRAIMOUDIP24-311 Redox regulation of Ku DNA-binding activity by glucose 6 phosphate dehydrogenase: Implications in DNA double strand break repair and cell survival.
Ayene, Iraimoudi1, Mauldin, Stanley2, Stamato, Thomas2, Biaglow, John1, Tuttle, Stephen1, Koch, Cameron1, 1 2
FULL ABSTRACT
AZINOVIC, IGNACIOP28-377 Relationship between tumor clonogenic fraction, PCNA index and S-phase fractionraction .
Azinovic, Ignacio 1, Gerweck, Leo2, 1 2
FULL ABSTRACT
AZUMA, CHIEKOP21-266 The relationship between hypoxia and proliferation in canine solid tumors .
Thrall, Donald1, Azuma, Chieko1, Raleigh, James2, Rosner, Gary3, 1 2 3
FULL ABSTRACT
AZUMA, CHIEKOMS10-2 The relationship between hypoxia and proliferation in canine solid tumors .
Thrall, Donald1, Azuma, Chieko1, Raleigh, James2, Rosner, Gary3, 1 2 3
FULL ABSTRACT
AZUMA, YOSHIP28-381 Hypoxia, differentiation and MT mRNA expression in squamous cell carcinomas.
Raleigh, James1, Azuma, Yoshi1, Chou, Shu-Chuan1, Varia, Mahesh1, 1
FULL ABSTRACT
AZZAM, EDOUARDP29-389 Rapid Activation of Stress-Related kinases in the Bystander Response of Human Cells to Low Fluences of -Particles.
Azzam, Edouard1,2, de Toledo, Sonia1,2, Little, John1, 1 2
FULL ABSTRACT

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