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G 2 ASSAYP25-266 Elevated G 2 chromosomal radiosensitivity observed in patients with benign and malignant prostate conditions.
Benign Prostatic hyperplasia, Prostate carcinoma, radiosensitivity, G 2 assay
FULL ABSTRACT
G 2 ASSAYMS07-3 Elevated G 2 chromosomal radiosensitivity observed in patients with benign and malignant prostate conditions.
Benign Prostatic hyperplasia, Prostate carcinoma, radiosensitivity, G 2 assay
FULL ABSTRACT
G2 DELAYP16-149 Hypoxic tumor cells remain competent for DNA repair.
DNA repair, Hypoxia, G2 Delay, 53BP1
FULL ABSTRACT
G2 ARRESTP15-145 A role of filamin-1 in the adaptation of G2 arrest following irradiation.
BRCA2, filamin, G2 arrest, cell cycle checkpoint
FULL ABSTRACT
G2 ARRESTMS12-6 A role of filamin-1 in the adaptation of G2 arrest following irradiation.
BRCA2, filamin, G2 arrest, cell cycle checkpoint
FULL ABSTRACT
G2/M PHASP29-283 PKCdelta Overexpression Enhances Radiation Sensitivity via ERK1/2 Activation and Abolishing the Radiation Induced G2/M Arrest.
PKCdelta, EKR1/2, Radiosensitivity, Apoptosis, G2/M phas
FULL ABSTRACT
GCLCS16-2 Redox Sensitive Interactions Between Nrf2 and KIAAO132 (the human homolog of Keap1) Regulate Expression of GCLC, the Catalytic Subunit for gamma Glutamylcysteine Synthetase, the Rate Limiting Enzyme for the Synthesis of Glutathione.
GCLC, Redox, Nrf2, Keap1
FULL ABSTRACT
GIP08-61 Target switching in radiation induced gastrointestinal death of mice.
radiation, GI, mice, ceramide
FULL ABSTRACT
GTPASE ACTIVATING PROTEINP22-254 Characterization of parx, a novel gene induced by ionizing radiation and other genotoxic agents.
Ionizing Radiation, Gene Trapping, DNA Damage, GTPase Activating Protein
FULL ABSTRACT
GTPASE ACTIVATING PROTEINMS12-1 Characterization of parx, a novel gene induced by ionizing radiation and other genotoxic agents.
Ionizing Radiation, Gene Trapping, DNA Damage, GTPase Activating Protein
FULL ABSTRACT
GADD45S17-4 Roles for the Gadd45a gene in the maintenance of genomic stability and cell signaling.
p53, Gadd45, MAP kinase, growth control
FULL ABSTRACT
GEMCITABINEP13-118 Apoptosis and Gemcitabine-mediated radiosensitization.
Gemcitabine, apoptosis, radiosensitization
FULL ABSTRACT
GEMCITABINEP17-163 Gemcitabine selectively targets homologous recombination mediated DNA double strand break repair.
Gemcitabine, homologous recombination repair, non-homologous end-joining, radiosensitization
FULL ABSTRACT
GENE DELIVERYS09- Genetic Therapy Symposium.
Genetic Therapy, Radiosensitization, Radioprotection, Gene Delivery
FULL ABSTRACT
GENE EXPRESSIONP19-189 The effectiveness of low dose neutron exposure on induction of micronuclei.
Biomarkers, Gene Expression, Radiation, neutrons
FULL ABSTRACT
GENE EXPRESSIONP18-179 hTERT Associating with Telomeres Reduces Spontaneous Chromosome Damage and Enhances DNA Repair.
Telomere, Telomerase, Gene Expression, DNA repair
FULL ABSTRACT
GENE TRAPPINGP22-254 Characterization of parx, a novel gene induced by ionizing radiation and other genotoxic agents.
Ionizing Radiation, Gene Trapping, DNA Damage, GTPase Activating Protein
FULL ABSTRACT
GENE TRAPPINGMS12-1 Characterization of parx, a novel gene induced by ionizing radiation and other genotoxic agents.
Ionizing Radiation, Gene Trapping, DNA Damage, GTPase Activating Protein
FULL ABSTRACT
GENES07-4 Thermal Goals for Gene Therapy.
Thermally, Activated, Gene, Therapy
FULL ABSTRACT
GENE SILENCINGP22-233 Low dose -rays-induced changes in gene expression: possible involvement of post-transcriptional gene silencing.
CSB, Transcriptional, Post-transcriptional, Gene silencing
FULL ABSTRACT
GENE THERAPYP21-228 Soluble TGF- type II receptor gene therapy ameliorates acute radiation-induced pulmonary injury in rats.
Gene therapy, Radiation, TGF-, Pulmonary toxicity
FULL ABSTRACT
GENETIC THERAPYS09- Genetic Therapy Symposium.
Genetic Therapy, Radiosensitization, Radioprotection, Gene Delivery
FULL ABSTRACT
GENETICSWS02- Microenvironmental and genetic factors in the response of the haemopoietic system to ionising radiation.
Microenvironment, Genetics , Cellular interactions, p53 pathway
FULL ABSTRACT
GENOMIC INSTABILITYP19-194 Instability-Associated Chromosomal Rearrangements are Non-Randomly Distributed in Human Cells.
Genomic Instability, Chromosomal Rearrangements, Karyotypic Analysis
FULL ABSTRACT
GENOMIC INSTABILITYWS02- Lessons from the Multicellular World.
Carcinogenesis, Cell interactions, Genomic instability, Apoptosis
FULL ABSTRACT
GENOMIC-INSTABILITYS19-3 "Bystander-mediated genomic instability of individual radiation tracks".
Non-targeted Responses, Genomic-Instability, Bystander-Effects
FULL ABSTRACT
GENOMICSS20-1 Bioinformatics and Genome Sciences.
Bioinformatics, Genomics, Human Genome Project
FULL ABSTRACT
GIANT CELLSP31-312 Computerized video time lapse (CVTL) analysis of the formation and fate of giants cells in x-irradiated human bladder carcinoma EJ30 cells.
Giant cells, Clonogenic, Time lapse, Viability
FULL ABSTRACT
GINSENGP12-109 Ginseng reduced the micronuclei yield in lymphocytes after irradiation.
Ginseng, Micronuclei, Lymphocytes, Radiation
FULL ABSTRACT
GLIOBLASTOMAP16-151 Effect of EGFR overexpression and mutation in glioma cell lines on sensitivity to EGFR tyrosine kinase inhibitor Tarceva (OSI-774).
Tarceva, Glioblastoma, amplification, EGFR
FULL ABSTRACT
GLOMERULAR PERMEABILITYP36-358 Protective effect of a cyclic AMP analog on radiation-induced increase in glomerular permeability.
Radiation nephropathy, Glomerular permeability, Cyclic AMP, Cytoskeleton
FULL ABSTRACT
GLUCOSEL06-1 Glucose Deprivation-Induced Oxidative Stress in Human Cancer Cells: A Fundamental Defect in Metabolism?
Glucose, Oxidative Stress, Mitochondria, Hydrogen Peroxide
FULL ABSTRACT
GLUCOSE-6-PHOSPHATE DEHYDROGENASEP28-281 G6PD deficient cells exhibit an unique cross sensitivity to PDT and ionizing radiation.
Glucose-6-phosphate dehydrogenase, Redox, Photodynamic Therapy , Apoptosis
FULL ABSTRACT
GLUTATHIONE RECYCLINGWIP-384 Comparison of glutathione recycling capacity in the kidney between the radiation-resistant C3H and the radiation-sensitive C57BL/6 strains.
Radiation, Reactive Oxygen Species (ROS), Glutathione recycling, Radioresistant/radiosensitive
FULL ABSTRACT
GROWTH FACTORSP11-104 The cell kinetic basis for radioprotection of murine lung with keratinocyte growth factor.
Normal tissue cell kinetics, Growth factors, Radioprotection, Cytometry
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GAMMA IRRADIATIONP31-311 Ultrastructural effects of ionising radiation on primary cultures of rainbow trout skin.
gamma irradiation
FULL ABSTRACT
GAMMA KNIFEP08-68 The Effect of Estrogen on Radiation-induced Cataractogenesis.
cataracts, gamma knife, estradiol, lens
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GAMMA RAYSP34-330 Mechanism of DNA radiosensitization by bromouridine.
DNA damage, radiosensitizer, gamma rays, Bromouracil
FULL ABSTRACT
GAMMA RAYSMS12-4 Mechanism of DNA radiosensitization by bromouridine.
DNA damage, radiosensitizer, gamma rays, Bromouracil
FULL ABSTRACT
GAMMA RAYSP37-361 Media from AL cells exposed to rays (<6 Gy) does not alter survival but abolishes the decreased mutant induction normally seen with fractionated doses.
mutation, conditioned media, gamma rays
FULL ABSTRACT
GAP-JUNCTIONSS19-2 Mechanisms Underlying the Transmission of Stress from Irradiated to non-Irradiated Cells.
bystander effect, gap-junctions, connexin43, reactive oxygen species
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GDEPTMP04-38 A GDEPT strategy to enhance the efficacy of bioreductive drugs in combination with radiation.
gdept, bioreductive drug, cytochrome P450, x-ray inducible promoters
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GEMCITABINEP13-120 Treatment sensitivity of Gemcitabine-resistant human tumor cell lines.
gemcitabine, ionizing radiation, human tumor cells, cell survival
FULL ABSTRACT
GENE CONVERSIONS04-1 Roles of the yeast Rad51 ATPase in spontaneous and double-strand break-induced recombination.
dna repair, gene conversion, homologous recombination, saccharomyces cerevisiae
FULL ABSTRACT
GENE DELIVERYMP04-37 Tumor-specific drug delivery using non-pathogenic bacteria: an alternative to gene therapy approaches.
Clostridium, hypoxia, gene delivery, suicide gene
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GENE EXPRESSIONP25-263 Accelerating development of a quantitative real-time multiplex RT-PCR assay of multiple gene targets for biological dosimetry.
gene expression , biodosimetry, biomarkers, assay
FULL ABSTRACT
GENE EXPRESSIONP22-235 Low dose alpha radiation effects on cytokine gene expression.
gene expression, cytokines, alpha radiation, low dose effects
FULL ABSTRACT
GENE EXPRESSIONMP02-15 Requirement for double stranded RNA-dependent protein kinase (PKR) for expression of heat shock proteins during stress involves mRNA stabilization.
double stranded RNA-dependent protein kinase (PKR), heat shock proteins ( HSPs ) , gene expression, mRNA stabilization
FULL ABSTRACT
GENE EXPRESSIONMS05-6 Requirement for double stranded RNA-dependent protein kinase (PKR) for expression of heat shock proteins during stress involves mRNA stabilization.
double stranded RNA-dependent protein kinase (PKR), heat shock proteins ( HSPs ) , gene expression, mRNA stabilization
FULL ABSTRACT
GENE EXPRESSIONMS07-9 A study of gene expression patterns in radio-resistant and -sensitive breast cancer cells using cDNA microarray assays.
radiation resistance, cDNA microarray, gene expression
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GENE EXPRESSIONP22-237 Intratumor differences in gene expression of human cervical carcinomas.
cervical cancer, gene expression, microarray technology, intratumor heterogeneity
FULL ABSTRACT
GENE EXPRESSIONP35-352 Oxidative metabolism mediates bystander effects in -particle-irradiated normal human fibroblast cultures.
bystander effect, oxidative metabolism, alpha-particles, gene expression
FULL ABSTRACT
GENE EXPRESSIONP22-239 Radiation Induced Gene Expression in the Nematode C. elegans.
C. elegans, microarray, gene expression, high LET
FULL ABSTRACT
GENE EXPRESSIONP22-242 Assessment of Low Dose Ionizing Radiation Induced Changes in Gene Expression in Human Subjects.
low dose radiation, gene expression, human effects, microdosimetry
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GENE EXPRESSIONP22-243 Identification of Apoptosis and Cell Cycle Regulatory Genes by Expression Profiling Using cDNA Arrays .
apoptosis, cell cycle, gene expression, expression profiling
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GENE EXPRESSIONP22-244 The Global Response to Radiation in Prostate Adenocarcinoma C4-2 Cells.
expression profiling, cell cycle, gene expression, apoptosis
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GENE EXPRESSIONS20-4 Expression profiling and informatic analysis of radiation reponse.
gene expression, p53, microarray
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GENE EXPRESSIONS05-1 Gene expression in response to low dose ionizing radiation: A functional genomics approach.
gene expression, microarray, dose-rate
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GENE EXPRESSIONP22-252 A study of gene expression patterns in radio-resistant and -sensitive breast cancer cells using cDNA microarray assays.
radiation resistance, cDNA microarray, gene expression
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GENE EXPRESSION ARRAYSP22-231 Gene expression profiles of spinal cords from mice following exposure to x-rays.
gene expression profiles, x-ray irradiation, gene expression arrays, spinal cord
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GENE EXPRESSION PROFILESP22-231 Gene expression profiles of spinal cords from mice following exposure to x-rays.
gene expression profiles, x-ray irradiation, gene expression arrays, spinal cord
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GENE EXPRESSION PROFILINGP25-265 Gene expression profiling as a predictor of tumor response to radiation.
gene expression profiling, tumor response, radiation, risk assessment
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GENE REGULATIONP30-289 Identification of genes regulated by hypoxia in vivo.
hypoxia, laser capture microscopy, gene regulation
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GENE TARGETSP22-229 Detection of gene targets in irradiated MCF-7 cells.
gene targets, biological dosimetry, irradiation
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GENE THERAPYS09-4 MnSOD Plasmid Liposome Gene Therapy for Prevention of Irradiation Induced Organ Specific Injury.
gene therapy, liposome, irradiation
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GENE THERAPYS09-2 Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for local recurrence of prostate cancer.
gene therapy, replication-competent adenovirus, prostate cancer, radiation therapy
FULL ABSTRACT
GENE THERAPYMS04-1 A novel conditionally replicating adenovirus for nasopharyngeal carcinoma (NPC) gene therapy .
gene therapy, nasopharyngeal carcinoma, transcriptional targetting
FULL ABSTRACT
GENE THERAPYMP02-17 The roles of HSP110 and HSP70 in enhancing antigen-specific immune responses.
heat shock protein, human papilloma virus-16 E7, immunotherapy, gene therapy
FULL ABSTRACT
GENE THERAPYMS04-6 Efficacy of ionizing radiation combined with adenoviral-p16 gene therapy in nasopharyngeal carcinoma.
p16, tumour suppressor, gene therapy, nasopharyngeal carcinoma
FULL ABSTRACT
GENE THERAPYP21-224 Endostatin delivered by gene therapy improves in vivo tumor response to radiation.
gene therapy, endostatin, angiogenesis, adeno-associate virus
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GENE THERAPYP21-225 Radiosensitization is Not Increased with the Addition of Adenoviral-E2F-1 when Combined with Adenoviral-p53 Mediated Gene Transfer.
gene therapy, radiation, p53, E2F-1
FULL ABSTRACT
GENE THERAPYP21-226 Hypoxia-inducible Expression of BAX Delays the Growth of Human Brain Tumors In Vivo.
gene therapy, glioblastoma multiforme, hypoxia, BAX
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GENE THERAPYP21-227 Chimeric gene promoters responsive to ionizing radiation and hypoxia for use in cancer gene therapy.
gene therapy, radiotherapy, hypoxia, promoters
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GENE THERAPYS09-1 Novel adenoviruses for radiosensitization of CNS and head and neck tumors.
gene therapy, HSV-TK, glioma, EGFR
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GENE THERAPYMP04-40 A novel conditionally replicating adenovirus for nasopharyngeal carcinoma (NPC) gene therapy .
gene therapy, nasopharyngeal carcinoma, transcriptional targetting
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GENE THERAPYMP04-41 Efficacy of ionizing radiation combined with adenoviral-p16 gene therapy in nasopharyngeal carcinoma.
p16, tumour suppressor, gene therapy, nasopharyngeal carcinoma
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GENE THERAPYMP04-39 Adenovirus-mediated antisense Ku70 gene transfer increases the radiosensitivity of human malignant gliomas.
gene therapy, Ku protein, radiation sensitivity, heat shock
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GENE THERAPYS07-3 Thermal goals for gene therapy and liposomal drug delivery.
Thermal dose, liposomes, gene therapy
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GENE TRANSFERRC09 Gene Transfer Systems: In Approaches Toward Understanding Radiation Resistance and Radio-Sensitization.
gene transfer, somatic cell gene therapy, radiation biology
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GENE TRAPP13-127 Random functional knockout strategy to identify the genetic components of resistance to cytotoxic therapies.
tirapazamine, gene trap, hypoxia
FULL ABSTRACT
GENE TRAPMS07-7 Random functional knockout strategy to identify the genetic components of resistance to cytotoxic therapies.
tirapazamine, gene trap, hypoxia
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GENETIC BACKGROUNDP07-54 Comparison of immunomodulatory effects in strains of mice differing in susceptibility to high linear energy transfer (LET) radiation.
immunomodulation, lymphoid tissues, genetic background, erythrocytes
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GENETIC MARKERSWS08 Molecular and Genetic Markers in Clinical Radiation Oncology.
radiation sensitivity, molecular markers, genetic markers
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GENOME INSTABILITYL02 Double-strand Break Repair in Human Cells.
DNA repair, recombination, RAD51, genome instability
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GENOMIC INSTABILITYWS09 Delayed effects of radiation exposure: trans-generational, bystander and genomic instability.
delayed effects, transgenerational, bystander effect, genomic instability
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GENOMIC INSTABILITYMS05-7 The influence of low dose ionizing radiation on elevated endogenous free radical levels in transgenic growth hormone mice .
free radicals, low dose radiation, antioxidants, genomic instability
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GENOMIC INSTABILITYP09-70 Multiple Endpoints of Oxidative Stress in Chromosomally Unstable Clones.
oxidative stress, chromosomal instability, genomic instability, reactive oxygen intermediates
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GENOMIC INSTABILITYP14-131 Effects of different alleles of the tumor suppressor p53 transfected back into a p53-null human lymphoblastoid cell line on spontaneous and X-ray induced mutation.
p53, mutagenesis, genomic instability, thymidine kinase
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GENOMIC INSTABILITYS04- Genes affecting Radiosensitivity and Genome Instability: From Yeast to Man.
homologous recombination, genomic instability, radiosensitivity, genomics
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GENOMIC INSTABILITYP19-191 Multiple manifestations of radiation-induced genomic instability in mammalian cells.
genomic instability, skip mutation, microsatellite sequences, minisatellite sequences
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GENOMIC INSTABILITYP19-193 Genomic instability in TK6 cells after exposure to Cs-137 vs. Fe-56.
genomic instability, TK6 cells, Cs-137 radiation, Fe-56 radiation
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GENOMIC INSTABILITYP15-140 The development of multinucleated giant cells following low dose irradiation in p53-proficient human tumor cells correlates with diminished p21(WAF1) protein abundance.
ionizing radiation, p21(WAF1) cell cycle inhibitor, giant cells, genomic instability
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GENOMIC INSTABILITYP35-349 Investigation of radiation induced genomic instability, the bystander effect and DNA methylation changes.
methylation, bystander, genomic instability
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GENOMIC INSTABILITYP09-80 The influence of low dose ionizing radiation on elevated endogenous free radical levels in transgenic growth hormone mice .
free radicals, low dose radiation, antioxidants, genomic instability
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GENOMIC INSTABILITYS04-3 Role of the Rad51 paralogs in radiation sensitivity and genome stability.
genomic instability, Rad51 paralogs, chromosomal aberrations, cell cycle response to radiation
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GENOMIC INSTABILITYWS03 S-phase checkpoints and genomic instability.
S-phase, Cell cycle checkpoints, genomic instability
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GENOMIC INSTABILITYS18- DNA double-strand break repair by homologous recombination.
DNA Repair, Homologous Recombination, genomic instability
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GENOMIC INSTABILITYMS06-6 Investigation of radiation induced genomic instability, the bystander effect and DNA methylation changes.
methylation, bystander, genomic instability
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GENOMICSP16-150 Gamma irradation alters both the frequency and the spectrum of recurrent genomic copy number aberrations in mouse islet carcinomas.
microarray, genomics, mouse, model
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GENOMICSS04-2 Genomic approaches with budding yeast to identify new genes affecting radiosensitivity and genome instability.
genomics, S. cerevisiae, yeast, expression profiling
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GENOMICSS04- Genes affecting Radiosensitivity and Genome Instability: From Yeast to Man.
homologous recombination, genomic instability, radiosensitivity, genomics
FULL ABSTRACT
GERMLINE MUTATIONP14-133 Suppression of radiation-induced germline mutations in mice by the adaptive response.
germline mutation, adaptive response
FULL ABSTRACT
GIANT CELLSP15-140 The development of multinucleated giant cells following low dose irradiation in p53-proficient human tumor cells correlates with diminished p21(WAF1) protein abundance.
ionizing radiation, p21(WAF1) cell cycle inhibitor, giant cells, genomic instability
FULL ABSTRACT
GLIOBLASTOMA MULTIFORMEP21-226 Hypoxia-inducible Expression of BAX Delays the Growth of Human Brain Tumors In Vivo.
gene therapy, glioblastoma multiforme, hypoxia, BAX
FULL ABSTRACT
GLIOMAP26-274 Continuous inhibition of mTOR enhances the efficacy of radiation therapy in U87 glioma xenografts.
mammalian target of rapamycin, cytostatic therapy, fractionated radiation, glioma
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GLIOMAP15-138 Do Rolipram and 8 Bromo cAMP or 8 Chloro cAMP enhance cytotoxicity in Glioma cell lines through a cell cycle dependent mechanism?
radiosensitivity, glioma, rolipram, cell cycle
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GLIOMAS09-1 Novel adenoviruses for radiosensitization of CNS and head and neck tumors.
gene therapy, HSV-TK, glioma, EGFR
FULL ABSTRACT
GLIOMAP13-128 Role of p53 in the resistance of gliomas to BCNU and TMZ.
p53, glioma, MGMT, resistance
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GLIOMAMS07-5 Role of p53 in the resistance of gliomas to BCNU and TMZ.
p53, glioma, MGMT, resistance
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GLOMERULOSCLEROSISP08-65 Glomerulopathy in mice treated with whole-body irradiation and VEGFR2-blocking antibody.
radiation, anti-angiogenic treatment, glomerulosclerosis, VEGFR2
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GLUCOSE DEPRIVATIONP31-304 Low glucose enhances TRAIL-induced reduction of Akt expression: Involvement of caspase-3.
glucose deprivation, TRAIL, Akt, caspase-3
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GLUTAREDOXINP39-372 Role of glutaredoxin in metabolic oxidative stress-activated ASK1-MEK-MAPK pathway.
glutaredoxin, oxidative stress, redox state, ASK1-MEK-MAPK
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GOALSS07- Defining thermal goals for hyperthermia.
thermal, goals, hyperthermia, treatment
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GROWTH CONTROLS17-4 Roles for the Gadd45a gene in the maintenance of genomic stability and cell signaling.
p53, Gadd45, MAP kinase, growth control
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GROWTH FACTORP31-306 TGF-Beta1 mediates apoptosis and p53 response in irradiated mammary gland.
growth factor, cell fate, mammary gland, signaling
FULL ABSTRACT
GRP170MP02-14 Identification of Functional Domains of Grp170 by Use of Targeted Deletions.
grp170, heat shock protein, chaperone, deletion mutant
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GRP170S02-3 Microarray Analysis of the Effects of HSP110 and grp170 on Human Macrophages and Dendritic Cells.
hsp110, grp170, apc, dc
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GRP170MS11-9 Identification of Functional Domains of Grp170 by Use of Targeted Deletions.
grp170, heat shock protein, chaperone, deletion mutant
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GUANOSINEP20-197 Effect of structure on relative yields of 8-hydroxy-2'-guanosine in irradiated solutions of guanylic acid.
DNA, base damage, guanosine, guanylic acid
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GUANYLIC ACIDP20-197 Effect of structure on relative yields of 8-hydroxy-2'-guanosine in irradiated solutions of guanylic acid.
DNA, base damage, guanosine, guanylic acid
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