P410 Effects of Prozac™, fluoxetine, on reproductive and biochemical responses in Japanese Medaka. Weston, James*,1, Huggett, Duane1, Foran, Christy3, Brooks, Bryan4, Slattery, Marc2, 1 The University of Mississippi, Environmental Toxicology Research Program, University, MS, USA3 West Virginia University, Department of Biology, Morgantown, WV4 University of North Texas, Department of Biological Sciences, Denton, TX, USA2 The University of Mississippi, Department of Pharmacognosy, NCNPR, ECHR & RIPS, University, MS, USA

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P411 Effects of fluoxetine on development in the sea urchin Lytechinus variegatus. Slattery, Marc*,1, Foran, Christy2, Brooks, Bryan3, Weston, James4, 1 The University of Mississippi, School of Pharmacy, Department of Pharmacognosy, NCNPR, ECHR & RIPS, Oxford, MS, USA2 West Virginia University, Department of Biology, Morgantown, WV, USA3 University of North Texas, Department of Biological Sciences, Denton, TX, USA4 The University of Mississippi, Environmental Toxicology Research Program, Oxford, MS

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P412 Determination of Acidic Pharmaceuticals in the Great Lakes and Western Canadian Rivers by Gas Chromatography Negative-Ion Chemical Ionization Mass Spectrometry. Sverko, Ed*,1, Grabuski, Josey1, Struger, John2, Donald, David3, Backus, Sean1, 1 NWRI, Environment Canada, Burlington, ON, Canada2 Ecosystem Health Division, Environment Canada, Burlington, ON, Canada3 Environmental Conservation Branch, Environment Canada, Regina, SK, Canada

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P413 Resistance of wastewater microorganisms to triclosan. Reither, Laura1, Orvos, David*,1, 1 Sweet Briar College, Sweet Briar, VA

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P414 Toxicity of Fluoroquinolone Antibiotics on Aquatic Organisms. Robinson, April*,1, Lydy, Michael1, 1 Southern Illinois University, Carbondale, IL, USA

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P415 Influence of -adrenergic blockers on Daphnia magna heart rate and respiration. Dzialowski, Edward*,1, Brooks, Bryan1, Turner, Phil1, Huggett, Duane2, 1 University of North Texas, Denton, TX, USA2 The University of Mississippi, University, MS, USA

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P416 Model for Utilizing Human Safety and Pharmacological Data to Prioritize Environmental Safety Initiatives Associated With Human Pharmaceuticals. Huggett, Duane*,1, Cook, Jon1, Ericson, Jon1, Williams, Richard1, 1 Pfizer Global Research and Development, Groton, CT

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P417 Bench Scale System for Evaluating the Fate of Pharmaceuticals in Municipal Drinking Water Treatment Facilities. Bundy, Michael*,1, Doucette, William1, Ericson, Jon2, Hettenbach, Kevin2, Sims, Ron1, 1 Utah State University, Logan, UT, USA2 Pfizer Global Research and Development, Groton, CT, USA

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P418 Waterborne and sediment toxicity of fluoxetine to select organisms. Brooks, Bryan*,1, Turner, Philip1, Stanley, Jacob1, Weston, James2, Glidewell, Elizabeth1, Foran, Christy3, Slattery, Marc2, Huggett, Duane2, 1 University of North Texas, Denton, TX, USA2 The University of Mississippi, University, MS, USA3 West Virginia University, Morgantown, WV, USA

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P419 Trace Determination of Caffeine in Coastal Waters from the Florida Keys. Azua, Arlette*,1, Gardinali, Piero1, 1 Florida International University, Department of Chemistry / SERC, Miami, Florida, USA

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P420 Assessment and Management of Pharmaceuticals and Personal Care Products in the Canadian Environment. Servos, Mark1, Innes, Elizabeth2, Given, Joseph*,2, Ostapyk, Kim2, Topp, Ed3, McInnis, Rodney1, Starodub, Mary Ellen4, 1 National Water Research Institute, Environment Canada, Burlington, Ontario, Canada2 Health Canada, Ottawa, Ontario, Canada3 Agriculture and Agri-Food Canada, London, Ontario, Canada4 Toxicology Consultant, Burlington, Ontario, Canada

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P421 Preliminary GSK Model for Estimating POTW Removals for Pharmaceutical Compounds. Cunningham, Virginia*,1, Constable, David1, 1 GlaxoSmithKline, King of Prussia, PA, USA

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P422 Fathead Minnow Lifecycle Exposure to Methyltestosterone. Parrott, Joanne*,1, Baker, Mark1, Blunt, Beverly1, Hewitt, L, 1 Environment Canada, Burlington, CA, CANADA

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