P703 Construction of a DNA microarray with cDNAs expressed in the Japanese medaka (Oryzias latipes) brain. Nakayama, Kei*,1, Oshima, Yuji1, Tashiro, Kosuke2, Nagafuchi, Ken1, Kang, Ik Joon1, Kitano, Takeshi3, Kishida, Mitsuyo3, Mita, Kazuei4, Honjo, Tsuneo1, 1 Laboratory of Fisheries Environmental Science, Graduate School, Kyushu University, Fukuoka, Japan2 Laboratory of Molecular Gene Technics, Graduate School, Kyushu University, Fukuoka3 Department of Materials and Life Science, Graduate School of Science and Technology, Kumamoto University, Kumamoto, Japan4 National Institute of Agrobiological Sciences, Tsukuba, Japan

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P704 Silver Inhibits Estrogen Mediated Gene Transcription. Shaw, Joseph*,1, Davey, Jennifer1, Hamilton, Joshua1, 1 Dartmouth Medical School, Hanover, NH, USA

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P705 Conservation of a glutathione S-transferase that provides protection against oxidative injury in largemouth bass. Gallagher, Evan*,1, Pham, Robert1, Doi, Adriana2, Hughes, Erin1, 1 Dept of Physiological Sciences, University of Florida, Gainesville, Fl2 National Institute of Environmental Health Sciences, Research Triangle Park, NC

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P706 CYP1B mRNA expression and estrogen metabolism in channel catfish. Butala, Harshala1, Metzger, Christine1, Rimoldi, John1, Willett, Kristine*,1, 1 University of Mississippi, University, MS, USA

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P707 Measurement of Copper-Induced Stress in Pimephales promelas Using Gene Expression Profiles. Lewis, Solange*,1, Keller, Stephen1, Lattier, David2, Lazorchak, James2, Smith, Mark3, 1 Department of Biological Sciences, University of Cincinnati, Cincinnati, OH, USA2 USEPA, 26 West Martin Luther King Drive, Cincinnati, OH, USA3 SoBran, Inc., Cincinnati, OH, USA

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P708 The novel CDR-1 protein confers resistance to cadmium toxicity in C. elegans. Dong, Jie*,1, Freedman, Jonathan1, 1 Nicholas School of the Environment and Earth Sciences, Duke University, Durham, NC, USA

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P709 Tissue Specific Responses of Japanese Medaka (Oryzias latipes) to Endocrine Disruptors. Min, Jiho*,1, Gu, Man Bock1, 1 National Research Laboratory on Environmental Biotechnoloy, Kwangju Institute of Science & Technology, Kwangju, Republic of Korea

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P710 Development of Stress Specific Functional cDNA Microarray of Japanese Medaka fish for Environmental Stress Analysis. Gu, Man Bock*,1, Min, Jiho1, Park, Kyeong Seo1, 1 National Research Laboratory on Environmental Biotechnoloy, Kwangju Institute of Science & Technology, Kwangju, Republic of Korea

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P711 Assessing the impact of metals on microbial communities from a chronically metal-enriched estuary using pollution induced community tolerance (PICT) and terminal restriction fragment length polymorphism (T-RFLP). Ogilvie, Lesley*,1, Grant, Alistair1, 1 University of East Anglia, Norwich, Norfolk, England

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P712 Toxicity of novel organotellurium compounds. Sailer, Brian*,1, Liles, Nathan1, Dickerson, Sarah1, Chasteen, Thomas2, 1 Sam Houston State University Department of Biology, Huntsville, TX, USA2 Sam Houston State University Department of Chemistry, Huntsville, TX, USA

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P714 The Phenylpyrazole Insecticide Fipronil Causes Male Infertility in Meiobenthic Copepods: A Genetic Analysis of Target Loci. Cary, Tawnya*,1, Chandler, George1, Staton, Joseph1, Coull, Bruce1, 1 University of South Carolina, Columbia, SC, USA

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P715 Cloning of a pregnane X receptor (PXR) in Zebrafish (Danio rerio). Bainy, Afonso*,1, Stegeman, John2, 1 Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil2 Woods Hole Oceanographic Institution, Woods Hole, MA, United States

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P716 Development of Assays for Lipophilic Contaminant Impact on Brain Tumor Proliferation and Apoptosis. Rummer, Rebecca*,1, Foran, Christy1, 1 West Virginia University, Morgantown, WV, USA

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P717 Bullheads, tumors, biomarkers, and biomonitoring in Chesapeake Bay tributaries: Summary of surveys conducted from 1992 to 2002. Pinkney, Alfred*,1, Harshbarger, John2, May, Eric3, Melancon, Mark4, Reichert, William5, 1 U.S. Fish and Wildlife Service, Annapolis, MD2 George Washington University Medical Center, Washington, DC3 University of Maryland Eastern Shore, Princess Anne, MD4 USGS, Patuxent Wildlife Research Center, Laurel, MD5 NOAA, Seattle, WA

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P719 An Ecological Perspective of Genomics: Assessing Ecological Risk Through Partnerships. Benson, William1, Degitz, Sigmund2, Snape, Jason3, Taylor, George4, Tyler, Charles5, Versteeg, Donald*,6, 1 US Environmental Protection Agency, Pensacola, FL, USA2 US Environmental Protection Agency, Duluth, MN, USA3 AstraZeneca, Brixham, Devon, UK4 George Mason University, Fairfax, VA, USA5 Exeter University, Exeter, Devon, UK6 The Procter & Gamble Company, Cincinnati, OH, USA

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P720 Changes in Largemouth Bass (Micropterous salmoides) Gene Expression Following Acute Exposure to Nonylphenol. Sabo-Attwood, Tara*,1, Larkin, Patrick1, Denslow, Nancy1, 1 University of Florida, Gainesville, FL, USA

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P721 Effects of PCB 126 on Phase 2 enzymes in juvenile chickens. van den Hurk, Peter*,1, Bowerman, William1, 1 Clemson University, Pendleton, SC, USA

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P722 The Comparative Toxicogenomics Database (CTDTM). Mattingly, Carolyn*,1, Colby, Glenn1, Li, Jiaxin1, Forbush, Biff2, Towle, David1, Forrest, John2, Boyer, James2, 1 Mount Desert Island Biological Laboratory, Salsbury Cove, ME, USA2 Yale University, New Haven, CT

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P723 Increased kidney and testicular cell death after developmental exposure to 17-ethinylestradiol in medaka (Oryzias latipes). Weber, Lynn*,1, Balch, Gordon2, Metcalfe, Chris2, Janz, David1, 1 Oklahoma State University, Stillwater, OK, USA2 Trent University, Peterborough, ON

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P724 Metallothionien and glutamyl-cysteine ligase expression in metal-exposed small mammals . Barrus, Helene*,1, Srinouanprachanh, Sengkeo1, Hooper, Michael2, McMurray, Scott2, Cobb, George2, Kavanagh, Terrance1, 1 University of Washington, Seattle, WA2 Texas Tech University, Lubbock, TX

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P725 Comparison of AHR, ARNT, and AHRR Expression in Chemically-Treated and Envirornmentally-Exposed Atlantic Tomcod from Two Populations. Roy, Nirmal*,1, Duffy, Jessica1, Zarzecka, Margaret1, Wirgin, Isaac, 1 NYU School of Medicine, Tuxedo, NY, US

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P726 Alterations in the expression and inducibility of genes in the aryl hydrocarbon receptor (AhR) pathway in wild-caught killifish (Fundulus heteroclitus) from a creosote-contaminated site. Wassenberg, Deena*,1, Meyer, Joel1, Manke, Jeanette1, Karchner, Sibel2, Hahn, Mark2, Di Giulio, Richard1, 1 Duke University, Durham, NC, USA2 Woods Hole Oceanographic Institution, Woods Hole, MA, USA

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P727 Impact of Chromium and Zinc on the Biological Activity of Aromatic Hydrocarbons. Sorrentino, Claudio*,1, Chambers, Chris2, Courtenay, Simon3, Wirgin, Isaac1, 1 Nelson Institute of Environmental Medicine, NYU School of Medicine, Tuxedo, NY, U.S.A.2 Coastal Ecology Branch, NMFS - Howard Marine Sciences Laboratory, Highlands, NJ, U.S.A.3 Canadian Department of Fisheries and Oceans, Gulf Fisheries Centre, Moncton, New Brunswick, CANADA

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P728 Characterization of p53 gene response in rainbow trout exposed to environmental contaminants. Roberts, Aaron*,1, Schmit, Alison1, Oris, James1, 1 Miami University, Oxford, OH, USA

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P729 Cloning and characterization of cytochrome P450 1A (Cyp1A) gene from the self-fertilizing fish Rivulus marmoratus (Cyprinodontiformes, Rivulidae). Kim, Il-Chan1, Lee, Yong-Sung1, Lee, Jae-Seong*,2, 1 Department of Biochemistry, College of Medicine, Hanyang University, Seoul, South Korea2 Department of Environmental Science, Graduate School, Hanyang University, Seoul, South Korea

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P730 Cloning and characterization of vitellogenin gene from the self-fertilizing fish Rivulus marmoratus (Cyprinodontiformes, Rivulidae). Kim, Il-Chan1, Lee, Yong-Sung1, Lee, Jae-Seong*,2, 1 Department of Biochemistry, College of Medicine, Hanyang University, Seoul, South Korea2 Department of Environmental Science, Graduate School, Hanyang University, Seoul, South Korea

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P731 Molecular and cellular biomarker responses to pesticide exposure in juvenile Chinook salmon (Oncorhynchus tshawytscha) . Eder, Kai*,1,2, Leutenegger, Christian1, Koehler, Heinz2, Wheelock, Craig1, Hammock, Bruce1, Wilson, Barry1, Werner, Inge1, 1 University of California, Davis, California, USA2 University of Tuebingen, Tuebingen, Germany

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