PH04 Advances in Analysis and Measurements
Exhibit Hall
8:00 AM - Thursday
(PH009) Comparison of hexabromocyclododecane determinations using GC/MS and LC/MS/MS.
Zaruk, D, MacInnis, G, Marvin, C, Sverko, E,
ABSTRACT- Hexabromocyclododecane (HBCD) is an important constituent within the class of compounds known as brominated flame retardants. Its use is worldwide and has recently gained considerable amount of attention to the analysis of HBCD in the environment. Currently, little information exists on the comparative determinations of HBCD between the GC and LC instrument platforms. Due to its labile nature, HBCD can either isomerically transform or breakdown in the GC liner. The application of LC/MS/MS and GC-MS to the analysis of HBCD was compared using both standard solutions and field samples consisting of Detroit River suspended sediments. Replicate injections were made using GC injection temperatures of 180C, 215C and 260C. While the GC-MS did not afford isomer-specific analyses, this technique should offer simple and reliable measurements of the occurrence of total HBCD in a variety of environmental matrices. Meanwhile, the LC/MS/MS provided good sensitivity and separation between the three isomers, although further investigation is required to understand the signal suppression/enhancement phenomenon related to sample matrix effects. Data will be presented and evaluated in relation to the relative performance, robustness and accuracy of each instrument platform.
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