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PARENT SESSION 73 - Effects of Pharmaceuticals 8:00 AM to 6:30 PM, Wednesday, 15 May 2002 Exhibition Area
(73-04) Fate and effect of triclosan in the aquatic ecosystems. A risk assessment approach.
Ferrari, B.*,1, Paxeus, N.2, Pinto, G.3, Pollio, A.3, Andreozzi, R.3, Marotta, R.3, Vogna, D.3, Lyberatos, G.4, Garric, J.1, 1 CEMAGREF 3b, quai Chauveau, Lyon, France2 GRYAAB, Göteborg, Sweden3 University of Naples, Vincenzo Techio 80, Naples, Italy4 University of Patras, Patras, Greece
ABSTRACT- The presence of pharmaceuticals and active ingredients in personal care products in natural and drinking waters has been reported in recent years in the literature. Sewage treatment plants (STP) were pointed out as the major source of discharge for these compounds to the environment. An important substance group of environmental concern is antimicrobial agents commonly used in hospitals, industries and households, such as Triclosan (CAS 3380-34-5). Over the last 30 years, Triclosan (5-chloro-2-(2,4-dichlorophenoxy)-phenol) has become the most widely used bisphenol and its use as a preservative and disinfectant continues to increase. Several studies have demonstrated that Triclosan and its derivatives can now readily be detected in sediments, waters and aquatic biota. Even if it was detected at low concentrations, Triclosan could be considered as a potentially hazardous compound for the aquatic environment. In the framework of the European project REMPHARMAWATER, we present a complete set of data on Triclosan within a global integrated strategy of an aquatic risk assessment. This approach included exposure and effect assessment. Exposure data were obtained 1) by the measurement of the substance in effluents of European STPs, 2) by the evaluation of its biotic and abiotic degradation. Effect data were obtained by ecotoxicological tests performed on bacteria, algae, microcrustaceans and fishes. Finally, risk characterization has been performed in order to estimate the incidence of the adverse effect occurring in the aquatic compartment using the well-known Predicted Environmental Concentration (PEC)/Predicted No Effect Concentration (PNEC) ratio approach.
Key words: Triclosan, PNEC, Risk, PEC
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