PARENT SESSION

1B+C Abiotic Transformation
Hall 9
8:30 AM - 12:30 PM, Monday, 28 April 2003
Chair: Peijnenburg, W.¹, ¹
Co-chair: Jafvert, C.T.², Gombar, V.K.³, ^{2 3}

(MO9/8) Degradation of macrolides, salinomycin and tiamulin in liquid manure.

Schluesener, Michael¹, Bester, Kai¹, Spiteller, Michael ¹, ¹ Institute of Environmental Research, Dortmund, Germany

ABSTRACT- Antibiotics such as macrolides, ionophores and pleuromutilins are used to treat agricultural livestock, e.g. pigs and cattle. Three fields of application are significant: growth promoter (salinomycin and formerly the tetracyclines), treatment of infections in livestock (pleuromutilins, sulfonamides, ionophores and macrolides) and prevention of infections especially if pigs from different stables are brought together (pleuromutilins, sulfonamides, ionophores and macrolides). A typical pig farm in Germany grows about 800 pigs each 9 months. Depending on the kind of infections in the livestock about 1-5 kg active ingredients are used per compound during the feeding phase. The respective animals absorb most of the compounds quickly but they do excrete the compound after some days with excretion rates of 50-90% of the applied amount. Thus large quantities of these pharmaceuticals are transferred together with liquid manure to manure tanks. The final homogenate is dispersed on the fields after varying time periods. This study focuses on the persistence of the respective compounds in the manure tank. We present a 180 day degradation experiment of the commonly used antibiotics erythromycin, roxithromycin, salinomycin and tiamulin in liquid manure as well as the resulting half-lifes.

Key words: Degradation, Antibitotics, Manure, HPLC-MS/MS