|
2L - Immunotoxicity - genotoxicity - ED (WEP/103) Endosulphan induces changes in the ovarian activity in goats. Prasad, R.L1, Pal, A.K.1, 2, Sanwal, P.C.3, Sinku, R.P.1, Bose, K.K.1, ,, Pushpanjali1, Jadhao, S.B.2, 1 Faculty of Veterinary Science & Animal Husbandry,Birsa Agricultural University, Ranchi 834007, Bihar, India2 ARS, Central Institute of Fisheries Education, Mumbai 400061, M.S., India3 Indian Veterinary Research Institute, Izatnagar 243122, U.P., India ABSTRACT- This experiment evaluated the adverse effect of chronic endosulphan toxicity on ovarian activity of black Bengal goats. Adult 24 female goats were divided into three groups and were given through concentrate 0, 100 and 300 ppm endosulphan for 90 days. Daily ad lib roughage was provided. Examination by conventional vaginal smear method for oestrus cycle and reproductive behavior was done. Length of oestrus cycle was increased (P<0.01) concomitantly with the increase in the dose of pesticide exposure. The duration of heat was decreased significantly (P<0.01). The concentration of serum cholesterol was found to increased (P<0.01) from day 60. Serum progesterone was decreased (P<0.01) on day 90th. Changes in the hormonal imbalance were also exhibited by prominent male like behavior of animals. It was concluded that chronic and sub lethal doses of endosulphan causes endocrine disruption and affect the reproductive health by changes in the hormone levels in goats. Key words: Chronic toxicity, Endosulfan, Goats, Ovarian activity |
