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1H a/b/c - Pesticides, pharmaceuticals, perfluoroalkylated substances, antibiotics (WEP/15) Development of analytical procedures for Perfluorinated Organic Compounds (PFCs) determination in environmental samples. Alzaga, Roberto1, Bayona, Josep Maria1, 1 Environmental Chemistry Dept. IIQAB-CSIC, Barcelona, Catalonia, Spain ABSTRACT- Perfluorinated Organic Compounds (PFCs) have unique physical, chemical, and biological properties, specially related to the high stability of the carbon-fluorine bond. PFCs include a broad spectrum of compounds such as carboxylic acids, alcohols, sulphonates, sulfonamides, etc. PFCs have been used for more than 50 years, and are involved in different industrial processes and uses such as surfactants, polishers, surface protectors, pesticides, paper, photographs, etc. The Organization for the Economic Cooperation and Development (OECD) listed PFCs as a high-production-volume (HPV).Concern about the risk associated with their occurrence in the environment is growing, because they are ubiquitous, persistent, owing high bioaccumulation and biomagnification potential as well as their harmful effects. Although analytical methods exits for investigating some PFC, further development of analytical methods is required to get further knowledge in the occurrence in environmental matrices and the mechanisms of incorporation into food webs. Moreover, PFCs must be monitored in order to acquire basic data on physical/chemical properties, environmental fate and pathways, ecotoxicity, and mammalian toxicology. These data are needed because few reports on environmental properties are available in the open literature. In this work, modern sample treatment techniques such as solid-phase microextraction (SPME), pressurized fluid extraction (PFE) and supercritical fluid extraction (SFE) will be evaluated for PFC analyses, due to the higher selectivity and analysis time depending on the matrix evaluated. Due to their physico chemical properties, some PFCs are GC-amenable but some of them need a derivatization step (such as carboxylic acids), and the most polar compounds such as sulphonic derivatives require LC for their analysis. All these separation techniques are coupled with high selective detectors like ECD, MS, NICI-MS, MS-MS. However few attempts have been developed in order to test these sample preparation techniques for the PFCs determination. Therefore, the aim of this work is to explore these techniques for PFC determination in incurred environmental matrices and biota. Key words: sample treatment, PFCs, Environmental analysis |
