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1A - Environmental analytical methods (MOP/7) Analysis of polycyclic musks AHTN (Tonalide®) and their transformation products. During, Sonja 1, Hühnerfuss, Heinrich1, König, Wilfried 1, Sydnes, Leiv2, 3, Kallenborn, Roland3, Valdersnes, Stig2, 1 University of Hamburg, Hamburg, Hamburg, Germany2 University of Bergen, Bergen, Bergen, Norway3 Norwegian Institute for Air Research, Tromsø, Troms, Norway ABSTRACT- Enantioselective analyses of chiral transformation products of anthropogenic substances play a central role in environmental studies aiming at the ′fate of xenobiotics′. For example, AHTN [1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)-ethanone, Tonalide®] is a polycyclic musk which is being used extensively as synthetic fragrance in cosmetic products and detergents. Discharges via sewage treatment plants to river water have been reported. As a consequence, AHTN is accumulated effectively in fishes and other aquatic organisms. In the present work, potential transformation products of the chiral AHTN that exhibit one or two stereo-genic centres have been synthesised under controlled laboratory conditions. The enantiomers of these racemic transformation products have been separated in a standard mixture using a capillary GC column with a modified Key words: Tonalide®, polycyclic musk, transformation products of Tonalide®, enantiomeric separation |
-cyclodextrin stationary phase. This selective separation method coupled with sensitive detection techniques gives highly valuable information about the discrimination between enzymatic and non-enzymatic transformation processes in different environmental compartments, because enantiomeric excesses, i.e., enantiomeric ratios different from 1.0, indicate enzymatic transformation and/or enantioselective bioaccumulative processes.