Room 519-A | Sexual Dysfunction (ED) Monday, July 11, 2005 Time: 8:30 AM-10:30 AM |
Prevalence of comorbidity among men with ED in the MALES 2004 longitudinal cohort.
Eardley, Ian1, Niederberger, Craig2, Fisher, William3, Rosen, Raymond4, Sand, Michael*,5, 1 St James' University Hospital, Leeds, UK2 University of Illinois at Chicago, Chicago, IL, USA3 University of Western Ontario, London, Ontorio, Canada4 Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA5 Bayer Healthcare, West Haven, CT, USA
ABSTRACT- Objective: To characterize the prevalence of self-reported comorbid diseases in a cohort of men with erectile dysfunction (ED) followed for 3 years. Method: 808 men aged between 20 and 80 years with self-reported ED were recruited from the original Men's Attitudes to Life Events and Sexuality (MALES) 2004 cohort of 2912 men with self-reported ED from eight countries (USA, UK, Germany, France, Italy, Spain, Mexico, and Brazil), 30 months after the initial study. Self-reported comorbidities were assessed and compared with answers obtained from this cohort of 808 men in the 2001 survey. Results: There were statistically significant (p<0.001) increases in the proportion of men who self-reported diabetes (from 21% in 2001 to 30% in 2004), depression / anxiety (from 26% to 35%, respectively), and hypertension (from 44% to 51%, respectively), and non-significant increases in hypercholesterolemia (from 43% to 48%, respectively), and cardiovascular disease (CVD) / angina (from 26% to 29%, respectively) over the 30-month follow-up. Conclusion: Men with ED in this cohort report significant increases in comorbid illness over a 30-month period. These data provide further evidence that ED may be a sentinel for other vascular illness and suggest the need for awareness among clinicians of these comorbid associations. Further research to elucidate causality is needed.
Key words: erectile dysfunction, comorbidity, diabetes, depression, hypertension