PARENT SESSION
MINISYMPOSIUM X: Signaling Processes During the Periovulatory Period
Tuesday, July 31, 2001, 10:30 AM-12:00 PM
Univ Ottawa-UCU Auditorium
Chair: Eli Y Adashi
Speakers: Eli Y Adashi, Lawrence L Espey, Marco Conti

PERIOVULATORY GENOMICS: A GROWING DATA BASE.

Adashi, Eli¹, ¹

ABSTRACT- Mammalian ovulation remains a process of central importance to the maintenance of the species. It would appear that the pre-ovulatory cascade, subject to some modifications, has been conserved throughout the evolutionary tree. Divergence is primarily apparent in the post-ovulatory phase of the reproductive phase of the cycle, the two distinguishing categories being external versus internal fertilization. In an effort to delineate the genetic determinants of the ovulatory process, several groups have set out to identify the complete complement of genes involved. The technology employed primarily differential display, and subtractive suppressive hybridization. The species studied included the rat, the mouse, and the brook trout. This presentation will attempt to summarize the above body of information as well as any additional relevant contributions. There is every reason to believe that substantial new information will be generated now that the molecular determinants of the ovulatory cascade are being systematically unraveled. Representative References: Rebecca L. Robker, Darryl L. Russell, Shinya Yoshioka, S. Chidanada Sharma, John P. Lydon, Bert W. O'Malley, Lawrence L. Espey, JoAnne S. Richards. Ovulation: a multi-gene, multi-step process. Steroids 65 (2000) 559-570. Julien Bobe, Frederick William Goetz. A S100 homologue mRNA isolated by differential display PCR is down-regulated in the brook trout (Salvelinus fontinalis) post-ovulatory ovary. Gene 257 (2000) 187-194.

KEY WORDS: ovary, ovulation, reproduction