W228. DISTRIBUTION OF ACTIVE BETA-CATENIN IN NEONATAL PORCINE UTERINE TISSUES AFFECTED BY AGE AND EXPOSURE TO ESTROGEN AND RELAXIN. Masters, Regina¹, Crean, Bethany¹, Yan, Wenbo², Wiley, Anne¹, Bagnell, Carol², Bartol, Frank¹, ¹ Auburn University, Auburn, AL² Rutgers University, New Brunswick, NJ

M229. 2,2′–DICHLOROBIPHENYL DECREASES AMPLITUDE AND SYNCHRONIZATION OF UTERINE CONTRACTIONS THROUGH MAPK–MEDIATED PHOSPHORYLATION OF CONNEXIN43. Chung, Daesuk¹, Loch-Caruso, Rita¹, ¹ University of Michigan, Ann Arbor, MI

T230. PCB 50- AND TNF-INDUCED RELEASE OF ARACHIDONIC ACID AND PROSTAGLANDINS FROM LATE GESTATION RAT AMNION FIBROBLAST CELLS IS ASSOCIATED WITH INCREASED EXPRESSION OF CALCIUM INDEPENDENT PHOSPHOLIPASE A₂. Brant, Kelly¹, Caruso, Rita¹, Flatley, Ellen¹, ¹ University of Michigan, Ann Arbor, MI

W231. CHRONIC EXPOSURE TO THE ARYL HYDROCARBON RECEPTOR AGONIST 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN ACCELERATES REPRODUCTIVE SENESCENCE IN THE FEMALE RAT. Petroff, Brian¹, Franczak, Anita^{1, 2}, Valdez, Kelli¹, Mizinga, Kemmy¹, ¹ University of Kansas Medical Center, Kansas City, KS² University of Warmia and Mazury, Olsztyn, Poland

M232. USING ZEBRAFISH TO INVESTIGATE TCDD-INDUCED REPRODUTIVE TOXICITY. King Heiden, Tisha^{1, 2}, Grzybowski, Michael^{1, 2}, Carvan, Michael², Hutz, Reinhold ^{1, 2}, ¹ University of Wisconsin - Milwaukee, Milwaukee, WI² UWM Great Lakes WATER Institute, Milwaukee, WI

T233. EFFECTS OF GESTATIONAL AND NEONATAL EXPOSURE TO GENISTEIN ON THE DEVELOPMENTS OF PREPUBERTAL OVARY AND UTERUS IN FEMALE SPRAGUE- DAWLEY RATS. Kim, Soon Sun ¹, Lee , Rhee Da ¹, Rhee , Gyu-Seek¹, Kwack, Seung Jun ¹, Seok, Ji Hyun ¹, Lim, Kwon Jo ¹, Chung, Jin-Yong ², Kim, Jong-Min ², Cho, Dae Hyun ¹, ¹ National Institute of Toxicological Research, KFDA, Seoul, Korea² Dong-A University, College of Medicine, Busan, Korea

W234. GEOGRAPHIC VARIATION IN SEMEN QUALITY: META-ANALYSIS OF SEMEN QUALITY LITERATURE. Phillips, Karen¹, Walker, Mark^{1, 2}, Weselak, Mandy², ¹ University of Ottawa, Ottawa, ON, Canada² Ottawa Health Research Institute, Ottawa, ON, Canada

M235. LACK OF 4-VINYLCYCLOHEXENE MONOEPOXIDE-INDUCED OVOTOXICITY IN CYP 2E1 NULL MOUSE OVARIAN CULTURES. Rajapaksa, Kathila ¹, Sipes, I Glenn¹, Hoyer, Patricia ¹, ¹ University of Arizona, Tucson, AZ

T236. SAPK/JNK MEDIATES RAPID STRESS-INDUCED, DOSE-DEPENDENT APOPTOTIC AND MITOGENIC SUPPRESSION AND PROLONGED STRESS-INDUCED APOPTOSIS, CELL CYCLE ARREST AND DIFFERENTIATION IN PLACENTAL CELLS AND EMBRYOS. Zhong, Wenjing¹, Wang, Yingchun¹, Lewis, Jennifer¹, Trostinskaya, Anna¹, Wang, Fangfei¹, Xie, Yufen¹, Rappolee, Daniel¹, ¹ Wayne State University School of Medicine, Detroit, MI

W237. EFFECT OF ANDROGEN RECEPTOR BLOCKADE ON THE INDUCTION OF SPERMIATION FAILURE IN ADULT RATS. Pratis, Kyriakos¹, Beardsley, Amanda ¹, Balourdos, Georgia¹, Van Sinderen, Michelle ¹, Stanton, Peter¹, McLachlan, Rob¹, O'Donnell, Liza¹, ¹ Prince Henry's Institute of Medical Research, Melbourne, VIC, Australia

M238. PROGRESSION OF NEONATAL DIETHYLSTILBESTROL-INDUCED DISRUPTION OF THE HAMSTER (Mesocricetus auratus) TESTIS AND SEMINAL VESICLE. Hendry, William¹, Weaver, Benjamin¹, Naccarato, Teran¹, Khan, Shafiq², ¹ Wichita State University, Wichita, KS² Clark Atlanta University, Atlanta, GA

T239. EXPOSURE TO DIETHYL HEXYL PHTHALATE (DEHP) DELAYS PUBERTY AND REDUCES ANDROGEN-DEPENDENT TISSUE WEIGHTS IN LONG EVANS HOODED AND SPRAGUE DAWLEY MALE RATS. Gray, Leon¹, Howdeshell, Kembra^{1, 2}, Furr, Johnathan¹, Lambright, Christy¹, Stoker, Tammy¹, Noriega, Nigel¹, ¹ US EPA, Reseach Triangle Park, NC² North Carolina State University, Raleigh, NC

W240. CHANGES OF PLASMA LEVELS OF REPRODUCTIVE HORMONES IN ADULT MACAQUE MALE MONKEYS AFTER ORAL ADMINISTRATIONS OF DIETHYLSTILBESTROL (DES). Itoh, Mariko ¹, Takumi, Ken¹, Mori, Takuma¹, Kojima, Chihiro², Watanabe, Gen², Taya, Kazuyoshi², Hayashi, Motoharu¹, Takenaka, Osamu¹, Shimizu, Keiko¹, ¹ Primate Reseach Institute of Kyoto University, Inuyama, Aichi, Japan² Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan

M241. EFFECT OF FEED INTAKE LEVEL ON PROGESTERONE CONCENTRATIONS IN HOLSTEIN COWS. Vasconcelos, Jose Luiz¹, Santos, Ricarda², Perez, Gabriela¹, Araujo, Davi¹, Maciel, Ana Beatriz¹, Pereira, Everton T¹, Marquezini, Guilherme H¹, ¹ FMVZ - UNESP, Botucatu, SP, Brazil² FCAV - UNESP, Jaboticabal, SP, Brazil

T242. CHRONIC ADMINISTRATION OF THE ENVIRONMENTAL POLLUTANT BENZO[A]PYRENE DISRUPTS THE REPRODUCTIVE SYSTEM IN ADULT MALE RATS. Raychoudhury, Samir¹, Blake, Charles², ¹ Benedict College, Columbia, SC² University of South Carolina School of Medicine, Columbia, SC

W243. EFFECTS OF HEAT STRESS ON RNA POOLS WITHIN MATURING BOVINE OOCYTES. Payton, Rebecca¹, Edwards, J. Lannett¹, ¹ The University of Tennessee, Knoxville, TN

M244. EFFECTS OF DIETARY CARBOHYDRATE SOURCE ON OOCYTE/EMBRYO QUALITY AND DEVELOPMENT IN HIGH-YIELDING, LACTATING DAIRY CATTLE. Fouladi-Nashta, Ali¹, Gutierrez, Carlos², Garnsworthy, Phill¹, Webb, Robert¹, ¹ The University of Nottingham, Loughborough, UK² Universidad Nacional Autonoma de Mexico, Mexico City, Mexico

T245. AN IN VIVO VS. IN VITRO COMPARISON OF CHANGES IN GENE EXPRESSION DURING 4-VINYLCYCLOHEXENE DIEPOXIDE-INDUCED RAT OVARIAN FOLLICLE LOSS USING OLIGO ARRAY ANALYSIS. Fernandez, Shannon¹, Greer, Kevin¹, Hoying, Adam¹, Hoying, James¹, Hoyer, Patricia¹, ¹ University of Arizona, Tucson, AZ

W246. BODY WEIGHT, BODY CONDITION, LEPTIN AND LEPTIN RECEPTORS ARE ASSOCIATED WITH POSTPARTUM OVARIAN REACTIVATION IN ZEBU COWS. Giraldo Echeverri, Carlos¹, Montaño Orrego, Erika¹, Ruiz-Cortés, Tatiana¹, ¹ Universidad de Antioquia, Medellín, Colombia

M247. THE HERBICIDE LINURON REDUCES FETAL TESTOSTERONE PRODUCTION DURING BOTH IN UTERO AND IN VITRO EXPOSURES. Wilson, Vickie ¹, Lambright, Christy¹, Furr, Johnathan¹, Howdeshell, Kembra², Gray, Earl¹, ¹ U. S. EPA, Research Triangle Park, NC² North Carolina State University, Raleigh, NC

T248. METHOXYCHLOR CAUSES OXIDATIVE DAMAGE IN THE MOUSE OVARY. Gupta, Rupesh¹, Schuh, Rosemary¹, Fiskum, Gary¹, Flaws, Jodi¹, ¹ University of Maryland, School Of Medicine, Baltimore, MD

W249. FETAL PROGRAMMING: PRENATAL TESTOSTERONE EXCESS DISRUPTS FETAL ENDOCRINE MILIEU. Steckler, T¹, MohanKumar, P.S.², Phillips, D.J.³, Refsal, K.², Jackson, L.M.¹, Bartol, F.F.⁴, Padmanabhan, V.¹, ¹ University of Michigan, Ann Arbor, MI² Michigan State University, East Lansing, MI³ Monash Medical Centre, Clayton, VIC, Australia⁴ Auburn University, Auburn, AL

M250. REDUCED FEED-INTAKE IN SOWS DURING LACTATION AFFECTS EMBRYO SEX RATIOS AND SURVIVAL. Vinsky, Michael¹, Dixon, Walter¹, Foxcroft, George¹, ¹ University of Alberta, Edmonton, AB, Canada

T251. THE HERMAPHRODITIC FISH Rivulus Marmoratus (CYPRINODONTIFORMES, RIVULIDAE): A MODEL SPECIES FOR MOLECULAR AND ENVIRONMENTAL TOXICOGENOMICS. Lee, Young-Mi¹, Jung, Sang-Oun ¹, Lee, Jae-Seong ¹, ¹ Hanyang University Graduate School, Seoul, South Korea

W252. DOWNREGULATION OF PROGESTERONE BIOSYNTHESIS IN RAT GRANULOSA CELLS BY ADLAY (Coix lachryma-jobi L. var. ma-yuen Stapf.) BRAN EXTRACTS. Hsia, Shih-Min ¹, Chiang, Wenchang¹, Kuo, Yueh-Hsiung¹, Wang, Paulus S², ¹ National Taiwan University, Taipei, Taiwan, R.O.C.² National Yang-Ming University, Taipei, Taiwan, R.O.C.

M253. 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN ALTERS ESTRADIOL RELEASE FROM MONKEY OVARIAN FRAGMENTS IN VITRO. Conley, Lisa^{1, 2}, White, Gina³, Hutz, Reinhold¹, ¹ University of Wisconsin-Milwaukee, Milwaukee, WI² Milwaukee Area Technical College, Milwaukee, WI³ Carroll College, Waukesha, WI

T254. CYTOCHROME P450 1A2 AND 2C29 EXPRESSION IN THE MOUSE OVARY MAY BE REGULATED BY METHOXYCHLOR. Miller, Kimberly¹, Gupta, Rupesh¹, Flaws, Jodi¹, ¹ University of Maryland School of Medicine, Baltimore, MD

W255. THE PPAR AGONIST GEMFIBROZIL MODULATES TESTOSTERONE PRODUCTION IN VITRO AND IN VIVO IN MALE GOLDFISH, Carassius auratus. Cameron, Colin¹, Woodhouse, Amanda¹, Wenman, Christine¹, Moon, Thomas¹, Trudeau, Vance¹, ¹ University of Ottawa, Ottawa, ON, Canada

M256. REDUCTION IN OOCYTE FERTILIZABILITY AFTER EXPOSURE OF FEMALE RATS TO TRICHLOROETHYLENE, AN ENVIRONMENTAL TOXIN. Wu, Katherine ¹, Berger, Trish¹, ¹ University of California, Davis, CA

T257. EVOLUTION OF THE HOXA/WNT AXIS AND ESTROGEN REGULATION OF WNT7a EXPRESSION IN THE NEONATAL PORCINE UTERUS. Ho, Teh-Yuan¹, Yan, Wenbo¹, Wiley, Anne ², Bartol, Frank², Bagnell, Carol¹, ¹ Rutgers University, New Brunswick, NJ² Auburn University, Auburn, AL

W258. EFFECT OF FEED INTAKE LEVEL ON THE OXYTOCIN-INDUCED PGF2 RESPONSE IN HOLSTEIN COWS. Santos, Ricarda¹, Vasconcelos, José Luiz², Bertan, Claudia³, Sá Filho, Ocilon², ¹ FCAV - UNESP, Jaboticabal, SP, Brazil² FMVZ - UNESP, Botucatu, SP, Brazil³ FMVZ - USP, Pirassununga, SP, Brazil

M259. SHEAR STRESS CAUSES RAPID LETHALITY IN PREIMPLANTATION MOUSE EMBRYOS BY INDUCTION OF SAPK-MEDIATED APOPTOSIS; AFTER FERTILIZATION, A NOVEL FUNCTION OF THE ZONA PELLUCIDA IS TO PREVENT SHEAR STRESS-ASSOCIATED LETHALITY. Xie, Yufen¹, Rappolee, DA¹, Wang, Fangfei¹, Zhong, Wenjing ¹, Puscheck, Elizabeth ¹, Shen, Hayley ², ¹ Wayne State University, Detroit, MI² Clarkson University, Potsdam, NY

T260. EFFECTS OF PROPYLTHIOURACIL ON STEROIDOGENESIS IN RAT GRANULOSA CELLS. Cho, Yu- Min¹, Wu, Yu- Ching¹, Wang, Kai- Lee¹, Lee, Yin- Huei¹, Wang, Paulus S¹, ¹ National Yang- Ming University, School of Medicine, Taipei, Taiwan, R.O.C.

W261. IN VITRO MODEL FOR THE STUDY OF LEPTIN AND LEPTIN RECEPTORS: ASSOCIATION WITH PERIOVULATORY EVENTS AND STEROIDOGENESIS OF ZEBU COWS. Montano Orrego, Erika¹, Giraldo Echeverri, Carlos ¹, Ruiz-Cortes, Tatiana¹, ¹ Universidad de Antioquia, Medellin, Colombia

M262. USE OF LIQUID DIET ADMINISTRATION IN PRENATAL ALCOHOL STUDIES MAY INCREASE THE RISK OF FAILED PREGNANCY AND MATERNAL NEGLECT. Smith, Andrew¹, Chen, Wei-Jung¹, ¹ Texas A&M University, College Station, TX

T263. NEONATAL METHOXYCHLOR EXPOSURE INHIBITS FOLLICULOGENESIS AND STIMULATES MULLERIAN INHIBITING SUBSTANCE PRODUCTION IN THE RAT OVARY. Uzumcu, Mehmet¹, Yao, Ming¹, Baseri, Babak¹, ¹ Rutgers University, New Brunswick, NJ

W264. PROGESTOGENIC AND ANTI-PROGESTOGENIC EFFECTS OF HYDROXYFLUTAMIDE ON THE UTERINE CaBP-9k mRNA AND PROTEIN EXPRESSIONS IN IMMATURE MICE. Ji, Youn-Kyu¹, Choi, Kyung-Chul², Jeung, Eui-Bae¹, ¹ Chungbuk National University, Cheongju, Chungbuk, Republic of Korea² University of British Columbia, Vancouver, BC, Canada

M265. EFFECTS OF CIS- AND TRANS-OCTADECENOIC ACIDS ON PHORBOL ESTER-INDUCED PROSTAGLANDIN F₂ PRODUCTION IN BOVINE ENDOMETRIAL CELLS. Rodriguez-Sallaberry, Carlos¹, Caldari-Torres, Cristina¹, Johnson, Elizabeth¹, Badinga, Lokenga¹, ¹ University of Florida, Gainesville, FL

T266. EFFECT OF SUPPLEMENTAL FATS ON OOCYTE QUALITY AND EMBRYO DEVELOPMENT IN LACTATING HOLSTEIN DAIRY COWS IN SUMMER. Bilby, Todd¹, Block, Jeremy¹, Sa Filho, Ocilon ¹, Silvestre, Flavio¹, do Amaral, Bruno¹, Hansen, Peter¹, Staples, Charles¹, Thatcher, William¹, ¹ University of Florida, Gainesville, FL

W267. BISPHENOL A INCREASE STEROIDAL HORMONE SECRETION OF TESTES. Gharravi, Anneh¹, Ghorbani, Rostam¹, Khazaei, Mozaffar¹, Al Agha, Mohsen¹, Ghasemi, Jahanbakhsh², Sayadi, Parviz¹, Pourmotabbad, Ali ¹, ¹ Kermanshah University of Medical Science, Kermanshah, Iran² Razi University, Kermanshah, Iran

M268. EFFECTS OF NONYLPHENOL EXPOSURE ON THE RELEASE OF TESTOSTERONE FROM RAT LEYDIG CELLS IN VITRO. Wang, Paulus ¹, Huang, Wei-Ju¹, Huang, Guey-Shyang¹, Cheng, Shao-Chi¹, Wang, Kai-Lee¹, Wu, Ching-I¹, Lee, Yin-Huei¹, ¹ National Yang-Ming University, School of Medicine, Taipei, Taiwan, ROC

T269. DISRUPTION OF OVARIAN FUNCTION BY SUBCHRONIC INHALED BENZO(A)PYRENE. Archibong, Anthony¹, Ramesh, Aramandla¹, ¹ Meharry Medical College, Nashville, TN

W270. A SINGLE INJECTION INTO IMMATURE RATS IS A USEFUL AND SENSITIVE TOOL TO DETECT AN ESTROGENICITY OF ESTROGENIC CHEMICALS RELATED TO THE INDUCTION OF CALBINDIN-D9k IN THE UTERUS THROUGH ESTROGEN RECEPTOR-DEPENDENT PATHWAY. Dang, Vu Hoang¹, Choi, Kyung-Chul², Hyun, Sang-Hwan¹, Jeung, Eui-Bae¹, ¹ Chungbuk National University, Cheongju, Chungbuk, Republic of Korea² University of British Columbia, Vancouver, BC, Canada

M271. THE EFFECT OF BCL-2 OVEREXPRESSION IN MICE ON OVOTOXICITY CAUSED BY 4-VINYLCYCLOHEXENE. Flaws, Jodi¹, Marion, Sam², Miller, Kimberly¹, Christian, Patricia², Hoyer, Patricia ², ¹ University of Maryland, School of Medicine, Baltimore, MD² University of Arizona, Tucson, AZ

T272. EICOSAPENTAENOIC ACID AND PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA REGULATE ENDOMETRIAL PROSTAGLANDIN F₂ PRODUCTION THROUGH DISTINCT SIGNALING MECHANISMS IN BOVINE ENDOMETRIAL CELLS. Caldari-Torres, Cristina¹, Rodríguez-Sallaberry, Carlos¹, Johnson, Elizabeth¹, Badinga, Lokenga¹, ¹ University of Florida, Gainesville, FL

W273. EFFECTS OF FEEDING FLAXSEED ON CYCLOOXYGENASE 2 (COX-2) AND PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) DELTA AND GAMMA mRNA LEVELS AT THE TIME OF MATERNAL RECOGNITION OF PREGNANCY IN HOLSTEIN COWS. Palin, Marie-France¹, Brochu-Gaudreau, Karine¹, Beaudry, Danièle¹, Small, Julie², Petit, Hélène¹, ¹ Agriculture and Agri-Food Canada, Dairy and Swine Research and Development Centre, Lennoxville, QC, Canada² Agriculture and Agri-Food Canada, Brandon Research Centre, Brandon, MB, Canada

M274. EFFECT OF SIMAZINE ON MALE REPRODUCTIVE DEVELOPMENT IN THE RAT. Stoker, Tammy¹, Buckalew, Angela¹, Ferrell, Janet¹, Cooper, Ralph¹, ¹ U.S. EPA, Research Triangle Park, NC

T275. STUNTED MOUSE MAMMARY GLAND DEVELOPMENT, IN THE ABSENCE OF BODY WEIGHT EFFECTS, FOLLOWING PRENATAL EXPOSURE TO PFOA. White, Sally¹, Rayner, Jennifer ¹, Hines, Erin², Thibodeaux, Julie², Fenton, Suzanne², ¹ University of North Carolina, Chapel Hill, NC² US EPA, Research Triangle Park, NC

W276. EFFECTS OF ENVIRONMENTAL TOBACCO SMOKE ON RHESUS MONKEY SPERM FUNCTION. Hung, Pei-hsuan¹, VandeVoort, Catherine¹, ¹ University of California, Davis, CA